| Exosomes | Microvesicles | Apoptotic bodies | Ref | |
|---|---|---|---|---|
| Size | 40–100 nm | 150–1000 nm | > 1000 nm | [16,17,18] |
| Composition |
ProteinsLipids RNAs |
ProteinsLipids RNAs |
DNA fragments Degraded proteins Micronuclei Cell organelles | [19, 20] |
| Origin | Multivesicular bodies | Plasma membrane | Plasma membrane, cellular fragments | [21] |
| Release | Exocytosis of MVBs | Budding from plasma membrane | Cell shrinkage and death | [21] |